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If oral antidepressants have not successfully treated your depression symptoms, you may have other options. Our team of psychiatrists at Williamsburg Therapy Group are accepting new patients for consultation appointments. If you are a candidate for Spravato (Esketamine) therapy in Brooklyn, NY, we will help you get confirmation about insurance coverage before starting treatment. We can administer Spravato nasal spray and provide observation in a safe, comfortable, and relaxing environment in our office in North Williamsburg.
Spravato is an FDA-approved nasal spray that can be an effective treatment option for some patients with major depressive disorder who aren't responding to traditional antidepressant medications.
Rigorously studied in clinical trials and FDA-approved for clinical use, Spravato therapy may be able to help those with chronic, severe, and treatment-resistant depression finally find relief.
Spravato, also known as Esketamine treatment, works differently than oral antidepressants. The antidepressant effects are usually felt faster compared to traditional oral antidepressants.
Spravato targets the N-methyl-D-aspartate (NMDA) receptor. NMDA is a receptor of glutamate, the primary excitatory neurotransmitter in the human brain. NMDA receptors play an integral role in regulating the brain's ability to build and maintain neural pathways. The process of creating and reinforcing new neural pathways is called neuroplasticity.
While the cause of depression is not fully understood, one compelling theory is that a reduction in maintained neuroplasticity is a factor. Spravato binds to NMDA receptors in a way that encourages neuroplasticity.
Unlike intravenous (IV) ketamine infusions, Spravato (esketamine) is FDA-approved and can be covered by most health insurance policies.
Ketamine and esketamine are closely related. Esketamine is the "S" enantiomer of ketamine, meaning it's a left-handed reflection of the ketamine molecule. Because esketamine is essentially ketamine with a slightly different blueprint, it can be suspended in a fluid and administered nasally.
In general, yes. The use of Spravato in patients with depression has been rigorously studied in clinical trials and is approved by the FDA.
Although no medication is without some possible risks, the FDA has determined that for qualified patients, the benefits of treatment with Spravato for depression outweigh the risks. Combined with the expertise and supervision of a medical professional, the overall risks are low.
Your individual experience with the benefits of Spravato may vary, but here are some general guidelines:
Compared to oral antidepressants, many patients report little to no significant side effects with Spravato. Some potential side effects that may occur right after the administration of Spravato include the following:
If you're feeling intense side effects, tell your doctor. They will continue to supervise you until you are ready to leave. These side effects tend to go away within a few hours of treatment.
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